What are the possible side effects of epoetin alfa (Epogen, Procrit, Retacrit)? Call your physician for medical advice about any side effects. Epogen Side Effects SHARE: PRINT EMAIL UPDATE (5/21/2007) : The lawyers at Saiontz & Kirk, P.A. Consult your doctor before taking Epogen if pregnant or breastfeeding. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. are no longer reviewing or considering Epogen lawsuits on behalf of users who suffered from drugs side effects. There are few legitimate medical uses. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. The phase IV clinical study is created by eHealthMe based on reports (from sources including the FDA) of 93,264 people who take Epogen/procrit and Aranesp, and is updated regularly. Epoetin alfa injection and epoetin alfa-epbx injection are biologic medications (medications made from living organisms). © 2005 - 2019 WebMD LLC. Common side effects include high blood pressure, headache, disabling cluster migraine (resistant to remedies), joint pain, and clotting at the injection site. We comply with the HONcode standard for trustworthy health information -. 4. Amgen, Thousand Oaks, CA. These side effects may go away during treatment as your body adjusts to the medicine. Epogen; Prices and coupons Skip prices section. Store Epogen in the refrigerator between 36°F to 46°F (2°C to 8°C). Mechanism of Action. If for sports or bodybuilding it is not smart. Your healthcare provider will talk with you about these risks. Epogen is not a drug that was designed for use in dogs, but it can nonetheless be very helpful in treating particular conditions that dogs suffer from. It can effect sexual function. CONDITIONS OF USE: The information in this database is intended to supplement, not substitute for, the expertise and judgment of healthcare professionals. Side effects: blood clots Treats anemia. NEUPOGEN prescription and dosage sizes information for physicians and healthcare professionals. Drug class: recombinant human erythropoietins, Anemia Associated with Chronic Renal Failure, pain, redness, or swelling in the arm or leg, sores, ulcers, or white spots on the lips or in the mouth, tenderness, pain, swelling, warmth, skin discoloration, and prominent superficial veins over the affected area, Blistering, peeling, or loosening of the skin, puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue, red skin lesions, often with a purple center. On November 30, 2006, reports came out that two studies in this months New England Journal of Medicine have called into question the overuse of drugs in … The target hemoglobin level is 12 g/dL, and the target should be achieved gradually. Below is a summary of known side effects for EPOGEN. Nausea, vomiting, constipation, and fatigue are the most common side effects of Epogen. How it's given: Epogen is given intravenously or as an injection 1 to 3 times per week. All rights reserved. Common side effects of Epogen include: • joint, muscle, or bone pain • fever • cough • rash • nausea • vomiting • soreness of mouth • itching • headache • redness and pain in the skin where Epogen shots were given These are not all of the possible side effects of Epogen. Medically reviewed by Drugs.com. Side effects are reported by people who take Epogen/procrit. Common side effects of Epogen in patients with kidney failure on dialysis include high blood pressure, headache, joint pain, and clotting at the injection site. Call your doctor for medical advice about side effects. Other side effects not listed may also occur in some patients. Rate Epogen to receive MedCheck, Discover best treatments based on user reviews of side effects, efficacy, health benefits, uses, safety and medical advice. High blood pressure is a common side effect of EPOGEN ® in people with chronic kidney disease. The study is created by eHealthMe based on 1 report from the FDA, and is updated regularly. Uses: Epogen is used to treat anemia, a lower than average number of red blood cells, that can be caused by chemotherapy. You may report side effects to the FDA at 1-800-FDA-1088. See below for a comprehensive list of adverse effects. "Product Information. The drug should be dosed using a specific target for hemoglobin levels (a measure of anemia). Other side effects not listed may also occur in some patients. Epogen/Procrit may cause serious side effects that can lead to death, including: For people with cancer: Your tumor may grow faster and you may die sooner if you choose to take Epogen/Procrit. On November 30, 2006, reports came out that two studies in this months New England Journal of Medicine have called into question the overuse of drugs in the treatment of anemia in kidney patients. Prices and coupons for 1 (1ml-of-2000-units-ml) vial of Epogen near . Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Novick on epogen side effects: It is an androgen. Your healthcare provider can give you a more complete list. Common side effects of Epogen in patients with kidney failure on dialysis include high blood pressure, headache, joint-pain, and clotting at the injection site. Available for Android and iOS devices. Authorised by the European Medicines Agency on 28 August 2007, it stimulates erythropoiesis (increasing red blood cell levels) and is used to treat anemia, commonly associated with chronic kidney failure and cancer chemotherapy.. Epoetin is manufactured and marketed by Amgen under the trade … The preservative benzyl alcohol has been associated with serious adverse reactions and death when administered intravenously to neonates and infants [see Warnings and Precautions (), Use in Specific Populations ()]. Most of the time it happens that they skip or avoid using any drug just because of the side effects associated with that. If for sports or bodybuilding it is not smart. Some common Epogen side effects are: Pain spreading to … For … Do not drive or operate heavy machinery until you know how Epogen affects you. In Summary. ferrous sulfate, pyridoxine, Revlimid, Aranesp, Procrit, Vitamin B6, lenalidomide, epoetin alfa, Retacrit, darbepoetin alfa. High blood pressure is a common side effect of EPOGEN ® in people with chronic kidney disease. Head-to-head comparisons of medication uses, side effects, ratings, and more. If you notice any other effects, check with your healthcare professional. Epogen can cause serious side effects, including heart attack, blood clots, or stroke. Source: FDA product label and Iodine pharmacists. Use the lowest dose of Epogen necessary to avoid RBC transfusions. Talk to your doctor for more information about side effects. If experienced, these tend to have a Severe expression, If experienced, these tend to have a Less Severe expression. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Cause gynecomastia, liver dysfunction. Note: This document contains side effect information about epoetin alfa. A healthcare professional should be consulted before taking any drug, changing any diet or commencing or discontinuing any course of treatment. Single-dose vials of Epogen should be used … Benzyl alcohol has been shown to cause brain damage, other serious side effects, and death in newborn and premature babies. Some of the dosage forms listed on this page may not apply to the brand name Epogen. Cerner Multum, Inc. "UK Summary of Product Characteristics." These are not all of the possible side effects of Epogen. Summary: We compare the side effects and drug effectiveness of Epogen/procrit and Aranesp. Epogen Side Effects. Aranesp vs Epogen – Comparison of Uses & Side Effects. Neupogen (filgrastim) can lower your risk of infection during chemotherapy, but it can cause a significant amount of bone pain. ESAs increase the risk of death, myocardial infarction, stroke, venous thromboembolism, thrombosis of vascular access, and tumor progression or recurrence.Chronic Kidney Disease:In controlled trials, patients experienced greater risks for death, serious adverse cardiovascular reactions, and stroke when administered erythropoiesis-stimulating agents (ESAs) to target a hemoglobin level greater than 11 g/dL.No trial has identified a hemoglobin target level, ESA dose, or dosing strategy that does not increase these risks.Use the lowest epoetin alfa-epbx dose sufficient to reduce the need for red blood cell (RBC) transfusions.Cancer:ESAs shortened overall survival and/or increased the risk of tumor progression or recurrence in clinical studies of patients with breast, non-small cell lung, head and neck, lymphoid, and cervical cancers.To decrease these risks, as well as the risk of serious cardiovascular and thromboembolic reactions, use the lowest dose needed to avoid RBC transfusions.Use ESAs only for anemia from myelosuppressive chemotherapy.ESAs are not indicated for patients receiving myelosuppressive chemotherapy when the anticipated outcome is cure.Discontinue following the completion of a chemotherapy course.Perisurgery:Due to increased risk of deep venous thrombosis (DVT), DVT prophylaxis is recommended. Doctors give trusted answers on uses, effects, side-effects, and cautions: Dr. Novick on epogen side effects: It is an androgen. Subcutaneous and Intravenous dosage. Procrit (epoetin alfa) is effective at treating low red blood cell count, but it might cause tumor growth and increased risk of blood clots. Some side effects are more common depending on the reasons for which you are taking PROCRIT ®. Muscle Spasm 6. "Product Information. It can effect sexual function. You may report side effects to the FDA at 1-800-FDA-1088. What is the difference between Retacrit and Epogen? EPO is produced naturally in the body, mostly by the kidneys. Common side effects of Epogen include: • joint, muscle, or bone pain • fever • cough • rash • nausea • vomiting • soreness of mouth • itching • headache • redness and pain in the skin where Epogen shots were given These are not all of the possible side effects of Epogen. Recommended Starting Dose. Side Effects and Risks of Erythropoietin. Serious Epogen side effects seem to be more common if treatment is too aggressive. 3. The most common side effects of epoetin alfa in patients with kidney failure on dialysis are:. Your blood pressure may go up or be difficult to control with blood pressure medication while taking EPOGEN ®. This can happen even if you have never had high blood pressure before. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to epoetin alfa: injectable solution, The most common adverse reaction was dose-dependent increase in blood pressure or aggravation of existing hypertension. It can take time for a drug to start working, or for some side effects to go away. Dangers of using EPOGEN from multiple-dose vials (which contain benzyl alcohol) in newborns, infants, and pregnant or breastfeeding women. O 0. Your blood pressure may go up or be difficult to control with blood pressure medicine while taking Epogen. Skip to what to expect section. Certain Epogen side effects are potentially serious, however, and should be reported to a healthcare provider immediately, including high blood pressure, seizures, allergic reactions, or an irregular heart rhythm. Aranesp (darbepoetin alfa) is effective at treating low red blood cell count, but it might cause tumor growth and raise risk of blood clots. Epogen is given at the same time as chemotherapy. Epogen/Procrit may cause serious side effects that can lead to death, including: For people with cancer: Your tumor may grow faster and you may die sooner if you choose to take Epogen/Procrit. Aranesp . If you use EPOGEN You may report side effects to FDA at 1 … Epogen Side Effects. These side effects are typically minor and, in most cases, do not require medical attention. >>READ WHY Individuals who are given Procrit injections at high doses could face an increased risk of serious and potentially fatal injuries as a result of Procrit side effects. It is the brand name of a drug called darbepoetin alfa, that belongs to a group of drugs called erythropoiesis-stimulating agents (ESAs). It is used in dogs and cats to treat anemia that occurs secondary to kidney failure. Applies to epoetin alfa: injection solution. It has also been shown to shorten the overall survival and/or increase the risk of tumor growth or recurrence in patients with certain types of cancer.